Publications since 2005 (peer reviewed)

1.     Di Giovanni S, Faden AI, Yakovlev A, Duke-Cohan JS, Finn T, Thouin M,  Knoblach SM, De Biase A, Bregman BS, Hoffman EP. Neuronal plasticity after spinal cord injury: Identification of a gene cluster driving neurite outgrowth. FASEB J. 2005 Jan;19(1):153-4. Epub 2004 Nov 02.

2.     Di Giovanni S, De Biase A, Yakovlev A, Finn T, Beers J, Hoffman EP, Faden AI. In vivo and in vitro characterization of novel neuronal plasticity factors identified following spinal cord injury.  J Biol Chem. 2005 Jan 21;280(3):2084-91. Epub 2004 Nov 01.

3.     Di Giovanni S, Movsesyan V, Ahmed F, Cernak I, Schinelli S, Stoica B, Faden AI. Cell cycle inhibition provides neuroprotection, reduces glial proliferation and scar formation after traumatic brain injury. Proc Natl Acad Sci U S A. Jun 7;102(23):8333-8. Epub 2005 May 27.

4.     Di Giovanni S٭, De Biase A٭, Knoblach SM٭, Molon A, Hoffman EP, Faden AI. Expression profiling of experimental spinal cord injury reveals a heterogeneous genomic response related to distance from impact and injury severity. Physiol Genomics 2005 Aug 11;22(3):368-81. Epub 2005 Jun 7. ٭ These authors equally contributed to this work.

5.     Cernak I, Stoica B, Byrnes KR, Di Giovanni S, and Alan I. Faden. Role of the Cell Cycle in the Pathobiology of Central Nervous System Trauma. Cell Cycle 2005 Sep;4(9):1286-93. Epub 2005 Sep 15.

6.     Molon A, Di Giovanni S, Yetrib H, Natale J, Hoffman EP. Functional recovery of glycine receptors in spastic murine model of startle disease. Neurobiol of Dis. 2006 Feb;21(2):291-304. Epub 2005 Sep 22.

7.     Ristori G, Cannoni S, Stazi MA, Vanacore N, Cotichini R, Alfò M, Pugliatti M, Sotgiu S, Solaro C, Bomprezzi R, Di Giovanni S, Figà Talamanca L, Nisticò L, Fagnani C, Neale MC, Cascino I, Giorgi G, Battaglia MA, Buttinelli C, Tosi R, and Salvetti M, for the Italian Study Group on Multiple Sclerosis in Twins. Multiple Sclerosis in Twins from Continental Italy and Sardinia: a Nationwide Study. Ann Neurol. 2006 Jan;59(1):27-34.

8.     Byrnes K, Garay J, Di Giovanni S, De Biase A, Knoblach SM, Hoffman EP, Movsesysan V, Faden AI. Expression of two temporally distinct microglia-related gene clusters after Spinal Cord Injury. Glia. 2006 Mar;53(4):420-33.

9.     Knights C, Catania J, Di Giovanni S, Muratoglu S, Perez R, Shwartzbeck A, Quong A, Zhang X, Beerman T, Pestell RG, and Avantaggiati ML. Distinct p53 acetylation cassettes differentially influence gene expression patterns and cell fate. J Cell Biol. 2006 May 22;173(4):533-44.

10.  Byrnes K, Stoica B, Di Giovanni S, De Biase A, Knoblach S, Hoffman E, Faden A.  The Role of Microglia and NADPH Oxidase in Traumatic Spinal Cord Injury. NeuroTherapeutics. 2006 Jul, 3 (3): 408. (Review).

11.  Di Giovanni S. Regeneration following Spinal Cord Injury, from experimental models to humans: where are we? Expert Opinion on Therapeutic Targets.  2006 Jun;10(3):363-76. (Review).

12.  Di Giovanni S, Knights C, Beers J, Mahadev Rao, Yakovlev A, Catania J, Avantaggiati ML, and Faden AI. The tumor suppressor protein p53 is required for neurite outgrowth and axon regeneration. EMBO J. 2006 Sep 6;25(17):4084-96.

13.  Annibali V, Di Giovanni S, Cannoni S, Giugni E, Bomprezzi R, Mattei C, Elkahloun A, Coccia EM, Alfò M, Orzi F, Ristori G, Salvetti M. Gene expression profiles reveal homeostatic dynamics during interferon-β therapy in multiple sclerosis. Autoimmunity. 2007 40 (1): 16-2.

14.  Byrnes K, Stoica BA, Fricke S, Di Giovanni S, Faden AI. Cell Cycle Activation Contributes to Post-Mitotic Cell Death and Secondary Damage after Spinal Cord Injury. Brain. 2007 Nov;130(Pt 11):2977-92.

15.  Nguyen T and Di Giovanni S. NFAT signaling in neural development and axon outgrowth. Int J Dev Neurosci. 2008 Apr;26(2):141-5. (Review).

16.  Tedeschi A, Nguyen T, Gaub P, Puttagunta R, Di Giovanni S. A p53-CBP/p300 transcription module is required for GAP-43 expression, axon outgrowth and regeneration. Cell Death Differ. 2009 Apr;16(4):543-54. Epub 2008 Dec 5.

17.  Tedeschi A. and Di Giovanni S. The non-apoptotic role of p53 in neuron biology: enlightening the dark side of the moon. EMBO Rep. 2009 Jun;10(6):576-83. Epub 2009 May 8. (Concept).

18.  Nguyen J, Linder R, Tedeschi A, Forsberg K, Green A, Wuttke A, Gaub P, Di Giovanni S. NFAT-3 is a transcriptional repressor of the growth associated protein 43 during neuronal maturation. J Biol Chem. 2009 Jul 10;284(28):18816-23. Epub 2009 May 14.

19.  Di Giovanni S. Molecular targets for axon regeneration: focus on the intrinsic pathways. Expert Opinion on Therapeutic Targets. 2009 Dec;13(12):1387-98. (Review).

20.  Tedeschi A, Nguyen T, Steele SU, Feil S, Naumann U, Feil R, Di Giovanni S. The tumour suppressor p53 transcriptionally regulates cGKI expression during neuronal maturation and is required for cGMP-dependent growth cone collapse. J Neurosci. 2009 Dec 2;29(48):15155-60.

21.  Lasseck J, Grieshaber P, Goebel U, Martin G, Thanos S, Di Giovanni S, Lagreze WA.Valproic acid-mediated neuroprotection and regeneration in injured retinal ganglion cells correlates with CREB induction and pERK1/2 activation. Invest Ophthalmol Vis Sci. 2010 Jan;51(1):526-34.

22.  Gaub P, Tedeschi A, Nguyen T, Schmandke A, Puttagunta R, Di Giovanni S. HDAC inhibition promotes neuronal outgrowth and counteracts growth cone collapse via CBP/p300 and P/CAF-dependent p53 acetylation. Cell Death Differ. 2010 Sep;17(9):1392-408.

23.  Puttagunta R, Schmandke A, Floriddia E, Fomin N, Gaub P, Ghyselinck NB, Di Giovanni S. RA-RARß counteracts myelin-dependent growth cone collapse and inhibition of neurite outgrowth via transcriptional repression of Lingo-1. J Cell Biol. 2011 193,1147-1156.

24.  Gaub P, Joshi Y, Naumann U, Wuttke A, Schnichels S, Heiduschka P, Di Giovanni S. The histone acetyltransferase p300 promotes intrinsic axonal regeneration. Brain. 2011 134, 2134-2148.

25.  Floriddia E, Nguyen T, Di Giovanni S. Chromatin Immunoprecipitation from Dorsal Root Ganglia Tissue following Axonal Injury. Journal of Visualized Experiments. 2011 Jul 20;(53).

26.  Erharhaghen J, Bartz M, Di Giovanni S, Melms A, Haarmeier T, Sieverding L. An unusual location of deep venous thrombosis associated with ischemic stroke and persistent foramen ovale. Case Rep Neurol. 2011 May;3(2):160-4.

27.  Di Giovanni S and Rathore K. P53-dependent pathways in neurite outgrowth and axonal regeneration. Cell Tissue Res. 2012 Jan 22. [Epub ahead of print]. (Review).

28.  Puttagunta R and Di Giovanni S. Retinoic acid signaling in axonal regeneration. Front Mol Neurosci. 2012 4:59. doi: 10.3389. [Epub ahead of print]. (Review).

29.  Quadrato G, Benevento M, Alber S, Jacob C, Floriddia EM, Tuan Nguyen N, Mohamed Y. Elnaggar, Pedroarena CM, Molkentin JD, Di Giovanni S. NFATc4 is required for BDNF-dependent survival of newborn neurons and for spatial memory formation in the adult hippocampus. PNAS. In press