Clinical Neurogenetics/Neurodegeneration - PhD position

The section Clinical Neurogenetics (Prof. Dr. L. Schöls) at the Hertie Institute for Clinical Brain Research offers a

PhD student position

In the PhD project, the pathophysiology of a novel genetic subtype of Hereditary Spastic Paraplegia, SPG36, will be studied. Hereditary Spastic Paraplegias comprise a group of hereditary motor neuron diseases. SPG36 is caused by a unique disease mechanism – a partial deletion of two neighboring genes – that leads to formation of a pathogenic fusion transcript.

The pathophysiological consequences of this fusion transcript will be studied using molecular genetic as well as protein biochemical methods. A zebra fish model for the disease will be developed in cooperation with the Max Planck Institute for Developmental Biology.

For further information please contact:
Dr. Rebecca Schüle
Hertie-Institut für Klinische Hirnforschung
Otfried-Müller-Str. 27
72076 Tübingen
Email: rebecca.schuele-freyer(at)uni-tuebingen.de
Tel: 07071 29 87609