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Clinical Genetics of Paroxysmal Neurological Diseases

 

Paroxysmal neurological disorders include a broad spectrum of clinical entities such as migraine, episodic ataxia or myotonia. The research group is focussed on the clinical genetics of epilepsies and paroxysmal dyskinesias, paroxysmal neurological disorders with overlapping clinical and pathophysiological features. More Info

Research projects
Clinical studies
Working Group members
Outpatient Clinic
  • Clinical and genetic analsysis of patients with epileptic encephalopathies and associated diseases
  • Pathophysiology-triggert precision medicine
  • Breathing disturbances in epilepsy patients
  • Development of a seizure detection system

 

Seizure detection system: A wearable device undependently from EEG analysis will be developed (funding: Bundesministerin für Wirtschaft und Energie und Karlsruher Institut für Technologie)

 

Vibes: A noninterventional study of Vimpat (Lacosamide) added to one baseline antiepileptic drug therapy in patients with brain tumor-related epilepsy (funding: UCB)

 

A multicenter, single-Arm, open-Label, post-marketing safety study to evaluate the risk of seizure among subjects with metastatic castration-resistant prostate cancer treated with Enzalutamide who are at potential increased risk of seizure (funding: Astellas Pharma)

 

EURAP
 A European registry to detect malformations and neuropsychological deficits on antiepileptic drugs during pregnancy

 

Valor: a double-blind,randomized,placebo-controlled parallel group,multicenter study to evaluate the efficacy and safety of  Lacosamide as adjunctive therapy for uncontrolled primary generalized tonic-clonic seizures in subjects with idiopathic generalized epilepsy (funding UCB)

 

A Phase 3, randomized, double-blind, placebo-controlled, crossover study to assess the efficacy and safety of UX007 in the treatment of movement disorders associated with Glucose Transporter Type 1 Deficiency Syndrome (Glut1 DS) (funding Ultragenyx)


 
Name
Department
Phone
Email
 Felicitas Becker
Felicitas Becker Physician
Clinical Genetics of Paroxysmal Neurological Diseases
 
 Ana Fulgencio Maisch
Ana Fulgencio Maisch Technician
Clinical Genetics of Paroxysmal Neurological Diseases
07071 29-87638 
 Christian Hengsbach
Christian Hengsbach Study Assistant
Clinical Genetics of Paroxysmal Neurological Diseases
07071 29-86525 
 Josua Kegele
Josua Kegele Physician
Clinical Genetics of Paroxysmal Neurological Diseases
07071 29-86588 
 Christina Lipski
Christina Lipski Physician
Clinical Genetics of Paroxysmal Neurological Diseases
 
 Katja Michaelis
Katja Michaelis study nurse
Clinical Parkinsons Disease Research
07071 29-80446 
 Sarah Rau
Sarah Rau Study Assistant
Clinical Genetics of Paroxysmal Neurological Diseases
07071 29-86525 
Prof. Dr. Yvonne Weber
Prof. Dr. Yvonne Weber Research Group Leader
Clinical Genetics of Paroxysmal Neurological Diseases
07071 29-80443 
Dr. Stefan Wolking
Dr. Stefan Wolking Physician
Clinical Genetics of Paroxysmal Neurological Diseases
07071 29-86525 

Outpatient clinic for epilepsy patients

 

In this outpatient clinic patients with epilepsy and differential diagnosis (like syncopies, psychogenic non-epileptic seizures, narcolepsy, dyskinesia) are advised concerning medication, social aspects and surgery.

For more details please check the homepage of the Dept. of Neurology of the University of Tübigen.

 

 

 

Research group leader
Prof. Yvonne Weber yvonne.weberuni-tuebingen.de Address

Center of Neurology
Hertie Institute for Clinical Brain Research
Department Neurology and Epileptology

Hoppe-Seyler-Straße 3
72072 Tübingen

Phone:  +49 (0)7071 29-80443 or
Phone:  +49 (0)7071 29-82048
Fax:  +49 (0)7071 29-4488