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Laying the foundations for tomorrow's medicine


  • Improving Outcomes for Brain Disease

    What distinguishes the HIH as a research institution? This question is explored in the short film “Improving Patient´s Outcome”. The clip was produced for the awareness campaign “Improving Outcomes for Brain Disease” of the European Academy of Neurology (EAN). In addition to the HIH, other internationally renowned institutions introduce themselves in the campaign. The campaign aims to raise the profile of Neurology, attract the best possible talent to work in this field, highlight excellence in research and practice, engage wider society on the complexity of brain disease, and influence policy makers and healthcare providers in order to improve funding for research.

    Click on the link to see the video.

  • Perception Control: How the Brain’s "Colliculum Superior" Helps to Thread a Needle

    We only see about one to two percent of our environment really sharp, which is the image section that falls into the visual pit (lat.: Fovea Centralis) of the retina. In order to perform tricky actions, such as threading a needle, we have to make very accurate tiny eye movements. This is the only way can we see the whole process in high resolution – and avoid piercing our finger. But how does our brain control these movements? Neuroscientists led by Professor Ziad M. Hafed at the Hertie Institute for Clinical Brain Research and the University of Tübingen have investigated this question. According to her results, the so-called Superior Colliculum in the brain stem plays a leading role, the researchers report in the current issue of the journal Current Biology. The findings help to better understand the visual system and its disorders.

    Read the complete press release (in German only)

  • HIH Researchers participate at Kinder-Uni-Forschertag 2019

    How does it feel to grow old? And what is dementia? These are the questions that Prof. Dr. Mathias Jucker, Dr. Deborah Kronenberg-Versteeg and further members will pursue at this year´s Kinder-Uni-Forschertag on July 6, 2019. Together with the young participants, Jucker and his team will take a look through the microscope to see what happens in the brain of Alzheimer's patients. They will also show how a mobile phone camera can be turned into a microscope that can also be used for further research at home. Using a simple age simulator, the little hobby researchers can also test what it feels like when you get older and your perception diminishes.

  • First TNC Research Day

    The TübingenNeuroCampus hosted the first TNC Research Day on June 27, 2019. More than 140 neuroscientists from Tübingen, Stuttgart and Switzerland joined the event and took part in various lectures, workshops, interactive sessions and poster presentations. PD Dr. Rebecca Schüle gave one of the keynote lectures on “Clinical Neuroscience in Tübingen”. HIH members Prof. Dr. Martin Giese, Dr. Daniel Häufle, Dr. Winfried Ilg and Dr. Simone Mayer made further contributions. The event was closed by an informal get together. “The TNC Research Day provided the Tübingen neuro community with the great opportunity to exchange information on current projects and possible future collaborations. The day proved to be very successful in my opinion,” says TNC co-initiator Prof. Dr. Thomas Gasser.

  • Physicians at the HIH among the leading medical doctors in Germany

    According to a recent survey by the news magazine “Focus-Gesundheit”, five physicians at the HIH are among the top medical doctors in Germany. They include Prof. Dr. Holger Lerche, Prof. Dr. Thomas Gasser, Prof. Dr. Dr. Ghazaleh Tabatabai, Prof. Dr. Yvonne Weber, and Dr. Markus Wolff. The judgement of colleagues and patients was the most important basis for the evaluation of the survey. In addition, the number of scientific publications and studies carried out were also included in the evaluation. 

    “Doctors at the university hospital are once again among the top physicians in Germany. This makes me proud, because the individual's achievements in health care and research benefit our patients and contribute to the excellent reputation of the University Hospital Tübingen,” says Prof. Dr. Michael Bamberg, Managing Medical Director and Chairman of the Executive Board of University Hospital Tübingen, being pleased with the entries of 54 Tübingen physicians in the Focus list of medical doctors.


  • Neurology and Stroke

    The Department of Neurology and Stroke has the main focuses in neurovascular medicine (vessel diseases of the brain, cerebral stroke), neuro-oncology (brain tumors, brain metastases), neuro-immunology (e.g., multiple sclerosis) and neuro-intensive medicine. ...more information

  • Neurodegenerative Diseases

    The Department of Neurodegenerative Diseases treats in-patients on a ward of about 20 beds and in several out-patient clinics. The clinical focus lies on neurodegenerative diseases such as Parkinson’s disease, the ataxias, spastic paraplegias, and dementias. ...more information

  • Neurology and Epileptology

    The Department of Neurology and Epileptology has a focus on epilepsy and other paroxysmal neurological disorders. In these diseases, the excitability of nerve cells temporarily changes either due to genetic or acquired defects. ...more information

  • Cognitive Neurology

    The Department of Cognitive Neurology provides consultant and outpatient neuropsychological care. Another clinical focus is the treatment of chronic dizziness in the interdisciplinary dizziness center “Südwestdeutsches Schwindelzentrum” operated in conjunction ..more information

  • Cellular Neurology

    The focus of the Department of Cellular Neurology lies on cellular and molecular mechanisms in the aging brain and age-related neurodegenerative diseases. Special emphasis is placed on Alzheimer's disease, the most common and severe form of senile dementia. ...more information

  • Independent Research Groups

    The independent research group at the HIH focuses on the physiology of learning and memory ...more information

Research groups

  • Neurology and Stroke

    Brain Networks and Plasticity

    The human brain possesses the remarkable capacity of reorganization, which is the basis for adapting to constantly changing environmental conditions. This plasticity is of paramount importance ...more information

  • Cognitive Neurology

    Neuropsychology of Action

    The Research Group "Neuropsychology of Action" is dedicated to investigations of human action control. We study clinical impairments of action control and their neural substrates in patients with brain damage ...more information

  • Cellular Neurology

    Experimental Neuroimmunology

    An immune response is part of most neurological diseases, and the development of late-onset Alzheimer's Disease (AD) has been linked to immune related genes and most recently also to epigenetic modifications. ...more information

  • Neurodegenerative Diseases

    Genetics of Parkinson's disease

    Parkinson's syndrome (PS) is the second most common neurodegenerative disease after Alzheimer's dementia. The vast majority of patients are ill with no apparent cause. ...more information

  • Cellular Neurology

    Section for Dementia Research

    The Section for Dementia Research of the Department of Cellular Neurology and the University Clinic for Psychiatry and Psychotherapy is headed by Prof. Dr. Christoph Laske. The section consists ...more information

  • Neurology and Epileptology

    Clinical Genetics of Paroxysmal Neurological Diseases

    Paroxysmal neurological disorders include a broad spectrum of clinical entities such as migraine, episodic ataxia or myotonia. The research group is focussed on the clinical genetics ...more information

  • Cognitive Neurology

    Neuro-Vestibular Diagnostics

    The complaint of dizziness is highly prevalent but remains often an enigma to the physician in daily practice. Serious diseases potentially accompanied by dizziness like stroke, multiple sclerosis ...more information

  • Cognitive Neurology

    Oculomotor Laboratory

    Playing video-games is a widely distributed leisure activity in our society. In order to estimate the consequences of video-game play, we study the details of eye movements and pupil light responses ... more information

  • Cellular Neurology

    Experimental Neuropathology

    Cerebral proteopathy is a unifying term for cerebral neurodegenerative diseases in which aggregated proteins are abnormally deposited in the brain. The hallmark proteopathy is Alzheimer's disease (AD) ...more information

  • Neurodegenerative Diseases

    Functional Neurogenomics

    Neurodegenerative disorders are associated in a proportion of cases with genetic risk and gene mutations. However, the vast majority of cases of Parkinson’s disease are sporadic and the disease is altogether heterogeneous in symptoms and pathology. ...more information

  • Independent Research Group

    Molecular Brain Development

    The mammalian neocortex is a highly complex and spatially heterogeneous structure, which has expanded significantly in mammalian evolution. Neocortical network function is at the heart of cognitive function ...more info

  • Neurology and Stroke

    Neurological B cell Immunology

    The research group “Neurological B cell Immunology” is focused on the role of B cells in neuro-inflammatory diseases including multiple sclerosis (MS) and ...more information

Research groups

  • Neurodegenerative Diseases

    Clinical Parkinson's Disease Research

    Parkinson's disease (PD) is the second most frequent neurodegenerative disorder after Alzheimer’s disease and affects about 1 to 2 % of individuals over the age of 65. The number is steadily increasing due to demographic changes in Western countries. ...more information

  • Cellular Neurology

    Molecular Imaging

    The Molecular Imaging group focuses on the visualization of Alzheimer's disease (AD) related changes in the brain of mouse models using in vivo multiphoton microscopy. A solid knowledge of the dynamics of amyloid lesions and ...more information

  • Neurology and Stroke

    Molecular Neurooncology

    Three to five of 100.000 people are annually diagnosed with a glioblastoma (GBM), the most malignant brain tumor in adults. Despite aggressive multimodal treatment including surgical resection and ...more information

  • Cellular Neurology

    Molecular Biomarkers

    Processes related to Alzheimer ́s disease (AD) and other age-related neurodegenerative diseases start many years before the onset of the first clinical symptoms. At the moment of the first clinical complaints, the disease has already caused ...more information

  • Neurology and Stroke

    Interdisciplinary Section of Neuro-Oncology

    The projects of the lab are focusing on the biology of brain tumors, especially with targeted individualized therapies, molecular mechanisms in the development of resistance and cell based therapy approaches ...more information

  • Neurology and Epileptology

    Translational Imaging

    The focus of our research group is the structural and functional imaging of neurological diseases with a particular focus on epileptology. We use multi-modal imaging techniques to improve the understanding of disease development ...more information

  • Neurodegenerative Diseases


    Dystonia is the third most common movement disorder, and mutations in a growing number of genes have been identified as causes for hereditary forms in many cases. The aim of the group, which brings together clinical experience ...more information

  • Neurology and Stroke

    Neurophonetics and Translational Neurorehabilitation

    The work group Neurophonetics and Translational Neurorehabilitation is based on a cooperation between the University of Tübingen and a neurological rehabilitation clinic (Fachkliniken Hohenurach). ...more information

  • Neurology and Stroke

    Stroke and Neuroprotection

    The research focus of our Stroke and Neuroprotection Laboratory is to find new and to optimize existing neuroprotective strategies ...more information

  • Neurology and Epileptology

    Experimental Epileptology

    Our research group is interested to unravel the mechanisms of well defined, mainly genetic, neurological, paroxysmal diseases, to understand correlations with clinical symptoms and to find new treatment options. ...more information

  • Cognitive Neurology

    Active Perception Lab

    Humans are tremendously reliant on the sense of vision to interact with their environment. Such interaction often involves the generation of motor outputs ...more information

  • Neurodegenerative Diseases

    Mitochondrial Biology of Parkinson’s Disease

    Neurodegenerative disorders are associated in a proportion of cases with genetic risk and gene mutations. However, the vast majority …more info

Research groups

  • Neurology and Epileptology

    Migraines and Primary Headache Disorders

    Our group aims at unraveling the molecular pathophysiology of migraine and other primary headache disorders. ...more information

  • Neurodegenerative Diseases

    Section for Clinical Neurogenetics

    Neurogenetic diseases like cerebellar ataxia, hereditary spastic paraplegia and leukodystrophy are rare disorders. ...more information

  • Neurodegenerative Diseases

    Systems Neurodegeneration

    Our research focuses on the investigation of the genetic basis, systems neuroscience and paradigmatic therapy approaches in ...more information

  • Cognitive Neurology

    Sensorimotor Lab

    The lab addresses a variety of topics that, at first glance, may look disparate. Yet, there is a common denominator ...more information

  • Neurodegenerative Diseases

    Genomic of Rare Movement Disorders

    Our group specializes in rare diseases. A disease is called rare, when it affects no more than 5 of 100,000 people. However, in the grand-scheme of things, rare diseases are not quite so rare ...more information

  • Cognitive Neurology

    Section for Computational Sensomotorics

    The Section for Computational Sensomotorics investigates theoretical principles in the perception and control of motor actions. Research is organized around three main topics ...more information

  • Neurodegenerative Diseases

    Genetics and Epigenetics of Neurodegeneration

    The recent advances in high-throughput genomic technologies have provided an unprecedented amount of genotype, expression and epigenetic data for many human disorders. ...more information

  • Cognitive Neurology

    Section for Neuropsychology

    The Section for Neuropsychology focuses on the investigation of spatial cognition and object recognition in humans. The current issues of our work comprise the action control and sensorimotor coordination ...more information

  • Neurodegenerative Diseases

    Functional Neurogenetics

    Age-related neurodegenerative diseases are a severe and increasingly worrisome burden for our aging population. Most of the chronic neurodegenerative diseases ...more information

  • Independent Research Groups

    Learning and Memory

    All organisms continuously have to adapt their behavior according to changes in the environment in order to survive. This is particularly important when learning to predict threatening or dangerous situations. ...more information

  • Cognitive Neurology

    Systems Neurophysiology Lab

    The overarching goal of our work is to understand the operating principles of the neocortex, a unique brain structure, which mainly evolved in mammals. There is clear evidence that the neocortex, in the broadest sense, endows the subject with cognitive capabilities. ...more information

  • Neurodegenerative Diseases

    Deep Brain Stimulation

    The working group aims to uncover mechanisms of action of deep brain stimulation therapy and to translate the pathophysiological insights into future developments. …more information

  • Cognitive Neurology

    Motor Control Modeling

    The research group „Multi-Level Modeling in Motor Control and Rehabilitation Robotics“ focuses on the generation and control of active biological movements. We develop ...more information

-Neurobiological Monday Colloquium 18:00 Agustin Ibanez (Experimental Psychology and Neuroscience, Institute of Cognitive Neurology (INECO), Buenos Aires)
Towards neurocognitive markers of neurodegenerative conditions: from brain atrophy networks to machine learning
Ort: HIH, Seminarraum 2.310
-Das Gehirn der Zukunft - KI & Medizin
Prof. Dr. Philipp Berens (University of Tübingen)
Prof. Dr. Linda Breitlauch (Trier University of Applied Sciences)
Dr. Nadine Giersch (German Center for Neurodegenerative Diseases, Magdeburg)
Dr. Roman Klinger (University of Stuttgart)

Presentation: Joachim Müller-Jung (FAZ)

6 pm
Location: University of Tübingen, Audimax

More infos: (in German only)
-Das Gehirn der Zukunft - KI & Ethik
Prof. Dr. Regina Ammicht-Quinn (University of Tübingen)
Prof. Dr. Markus Frings (Evang. Klinikum Niederrhein)
Dr. Christoph Peylo (Robert Bosch GmbH)
Prof. Dr. Michael Sedlmair (University of Stuttgart)

Presentation: Carsten Knop (FAZ)

6 pm
Location: University of Stuttgart, M 17.02 Tiefenhörsaal

More infos: (in German only)

Combining excellent research and patient care

Click on the image to watch the video

An exemplary connection between research and clinical care

The German Council of Science and Humanities recognizes the performance and academic excellence of theHertie Institute for Clinical Brain Research. The recommendation of the council is an excellent basis for the further development of the HIH. 

Press release by the German Council of Science and Humanities (Wissenschaftsrat)

Press release by the HIH