Laying the foundations for tomorrow's medicine

News

  • Dieter Janz Prize 2024

    Congratulations to Dr. Christian Boßelmann on winning the „Dieter Janz Prize 2024“ from the “Epilepsie-Stiftung Wolf“ and the German Society for Epileptology for his publication “Predicting functional effects of ion channel variants using new phenotypic machine learning methods” in PLOS Computational Biology.

    More information

  • Annual Report 2023

    The new annual report of the Hertie Center for Neurology for 2023 is now available for download. 

    The year 2023 was rich in successes, scientific findings, collaborations and prestigious awards. Thanks to the commitment and work of all our employees, we managed to pursue our ambitious goals. 

    You can download the annual report here

  • "Paper of the Month" Award of the Else Kröner-Fresenius Foundation

    Congratulations to Prof. Esther Kühn, head of the research group "Translational Imaging of Cortical Microstructure", on winning the "Paper of the Month" Award from the Else Kröner-Fresenius Foundation in May for her publication "Multimodal layer modelling reveals in vivo pathology in amyotrophic lateral sclerosis", recently published in BRAIN.

    More information

  • June 8, 2024 is World Brain Tumor Day

    On this occasion, Prof. Dr. Dr. Ghazaleh Tabatabai, Head of the Department of "Neurology and Interdisciplinary Neuro-Oncology", explains in an interview with the Hertie Foundation (GHS) which therapeutic approaches she is using in the fight against brain tumors, how she plans to combat metastasis in the meninges with a new immunotherapy study, and why medical progress sometimes cannot be immediately applied in treatment.

    Read the full interview (in German only)

  • 50th Anniversary of the Hertie Foundation

    Congratulations on the 50th anniversary of the Hertie Foundation (GHS)! For half a century, the foundation has made a significant contribution to society and has successfully implemented numerous projects and initiatives in the areas of “Gehirn erforschen” and “Demokratie stärken”.

    We would like to thank the GHS for the generous support since the Hertie Institute was founded over 20 years ago and wish a happy anniversary!

    Link to the GHS (in German only)

  • "Day Against Stroke" May 10, 2024

    Every year around 270,000 people in Germany suffer a stroke. If the first symptoms appear, such as sudden one-sided paralysis, numbness, speech or vision problems, every minute counts to prevent permanent brain damage.

    A race against time that Prof. Dr. Sven Poli, head of the “Stroke and Neuroprotection” lab in the Department of “Neurology and Stroke” at the HIH, wants to win with the help of new therapies.

    More information (in German)

  • Visit of Petra Olschowski, Minister of Science, Research and Arts

    New approaches in Alzheimer's therapy, advances in Neuro-oncology and the world's most valuable science prize for Parkinson's research: Researchers from the Hertie Center for Neurology presented their excellent work in brain research during the visit of Petra Olschowski, Minister of Science, Research and Arts for the State of Baden-Württemberg, on Monday, April 29, 2024 in Tübingen.

    More information (in German only)

  • "2024 Breakthrough Prize in Life Sciences" for Prof. Thomas Gasser

    Prof. Thomas Gasser, chair of the board of directors at the HIH and director of the “Department for Neurodegenerative Diseases”, has been awarded the “2024 Breakthrough Prize in Life Sciences” endowed with US$ 3 Mio, during the Prize Ceremony in LA, together with Ellen Sidransky and Andrew Singleton for discovering genetic risk factors for Parkinson’s disease.

    More information

  • “Doc Fischer” on SWR

    A SWR team from the health series “Doc Fischer” visited the HIH, the Neurological Clinic and the University Clinic for Neurosurgery for a tv report on the topic of epilepsy.
    Prof. Holger Lerche, head of the Department of “Neurology and Epileptology” at the HIH, together with Dr. Ulrike Hedrich-Klimosch (research group leader at the HIH), Dr. Silke Ethofer (senior physician at the University Clinic for Neurosurgery) and an epilepsy patient, were accompanied for a day with the camera.

    Watch it in the ARD Mediathek in German (starting from Min. 11:00)

Departments

  • Neurology and Stroke

    The Department of Neurology and Stroke has the main focuses in neurovascular medicine (vessel diseases of the brain, cerebral stroke), neuro-oncology (brain tumors, brain metastases), neuro-immunology (e.g., multiple sclerosis) and neuro-intensive medicine. ...more information

  • Neurodegenerative Diseases

    The Department of Neurodegenerative Diseases treats in-patients on a ward of about 20 beds and in several out-patient clinics. The clinical focus lies on neurodegenerative diseases such as Parkinson’s disease, the ataxias, spastic paraplegias, and dementias. ...more information

  • Neurology and Epileptology

    The Department of Neurology and Epileptology has a focus on epilepsy and other paroxysmal neurological disorders. In these diseases, the excitability of nerve cells temporarily changes either due to genetic or acquired defects. ...more information

  • Department of Neurology and Interdisciplinary Neuro-Oncology

    The Department of Neurology and Interdisciplinary Neuro-oncology (Director: Prof. Ghazaleh Tabatabai) is a department covering both inpatient and outpatient clinical care... More information

  • Neural Dynamics and Magnetoencephalography

    The Department of Neural Dynamics and Magnetoencephalography was founded in the year 2020 and Prof. Dr. Markus Siegel was appointed head of the department. ...more information

  • Cellular Neurology

    Our research focus is on the cellular and molecular mechanisms of brain aging and age-related neurodegenerative diseases, with a special emphasis on the pathogenesis of Alzheimer´s disease and other cerebral proteopathies ...more information

  • Independent Research Groups

    The independent research groups at the HIH focus on a variety of research topics ...more information

Research groups

  • Helfrich Lab

    Human Intracranial Cognitive Neurophysiology

    The goal of the Helfrich lab is to unravel the neural network mechanisms supporting higher cognitive functions  ...more info

  • Ziemann Lab

    Brain Networks and Plasticity

    The human brain possesses the remarkable capacity of reorganization, which is the basis for adapting to constantly changing environmental conditions. This plasticity is of paramount importance ...more information

  • Himmelbach Lab

    Neuropsychology of Action

    The Research Group "Neuropsychology of Action" is dedicated to investigations of human action control. We study clinical impairments of action control and their neural substrates in patients with brain damage ...more information

  • Neher Lab

    Experimental Neuroimmunology

    An immune response is part of most neurological diseases, and the development of late-onset Alzheimer's Disease (AD) has been linked to immune related genes and most recently also to epigenetic modifications. ...more information

  • Gasser Lab

    Genetics of Parkinson's disease

    Parkinson's syndrome (PS) is the second most common neurodegenerative disease after Alzheimer's dementia. The vast majority of patients are ill with no apparent cause. ...more information

  • Laske Unit

    Dementia Research Unit

    The Dementia Research Unit is a clinical research unit of the Department of Cellular Neurology and the Department of Psychiatry. It closely collaborates with the outpatient Memory Clinic. ...more information

  • Ilg Lab

    Oculomotor Laboratory

    Playing video-games is a widely distributed leisure activity in our society. In order to estimate the consequences of video-game play, we study the details of eye movements and pupil light responses ... more information

  • Jucker Lab

    Experimental Neuropathology

    Cerebral proteopathy is a unifying term for cerebral neurodegenerative diseases in which aggregated proteins are abnormally deposited in the brain. The hallmark proteopathy is Alzheimer's disease (AD) ...more information

  • Mayer Lab

    Molecular Brain Development

    The mammalian neocortex is a highly complex and spatially heterogeneous structure, which has expanded significantly in mammalian evolution. Neocortical network function is at the heart of cognitive function ...more info

  • Kowarik Lab

    Neurological B cell Immunology

    The research group “Neurological B cell Immunology” is focused on the role of B cells in neuro-inflammatory diseases including multiple sclerosis (MS) and... more information

  • Hauser Lab

    Advanced Cellular Models of Neurodegeneration

    The research group focuses on the development of cutting-edge cellular models for the study of monogenetic neurodegenerative diseases ...more info

  • Siegel Lab

    Neural Dynamics and Magnetoencephalography

    The central goal of the laboratory is to investigate how cognition and behavior emerges from dynamic interactions across widely distributed neuronal ensembles... more information

  • Hedrich-Klimosch Lab

    Experimental Neurophysiology of Channelopathies

    Our research group uses transgenic mouse models to investigate the molecular mechanisms of disease-associated variants in genes encoding neuronal ion channels. ...more information

Research groups

  • Kronenberg-Versteeg Lab

    Glial Cell Biology

    Glial cells are highly abundant in the mammalian brain, yet many questions regarding their development, function, and involvement in disease remain unanswered. ...more information

  • Brockmann Lab

    Clinical Parkinson's Disease Research

    Parkinson's disease (PD) is the second most frequent neurodegenerative disorder after Alzheimer’s disease and affects about 1 to 2 % of individuals over the age of 65. The number is steadily increasing due to demographic changes in Western countries. ...more information

  • Sevenich Lab

    Experimental Neuroonco-Immunology

    Research in this lab is focused on tumor immunology in brain cancer in particular brain metastasis ...more information

  •  Unit

    Käser Unit

    Molecular Biomarkers Unit

    Processes related to Alzheimer ́s disease (AD) and other age-related neurodegenerative diseases start many years before the onset of the first clinical symptoms. At the moment of the first clinical complaints, the disease has already caused ...more information

  • Gasser Lab

    Dystonia

    Dystonia is the third most common movement disorder, and mutations in a growing number of genes have been identified as causes for hereditary forms in many cases. The aim of the group, which brings together clinical experience ...more information

  • Poli Lab

    Stroke and Neuroprotection

    The research focus of our Stroke and Neuroprotection Laboratory is to find new and to optimize existing neuroprotective strategies ...more information

  • Lerche Lab

    Experimental Epileptology

    Our research group is interested to unravel the mechanisms of well defined, mainly genetic, neurological, paroxysmal diseases, to understand correlations with clinical symptoms and to find new treatment options. ...more information

  • Hafed Lab

    Active Perception Lab

    Humans are tremendously reliant on the sense of vision to interact with their environment. Such interaction often involves the generation of motor outputs ...more information

  • Fitzgerald Lab

    Mitochondrial Biology of Parkinson’s Disease

    Neurodegenerative disorders are associated in a proportion of cases with genetic risk and gene mutations. However, the vast majority …more info

  • Grimm Lab

    Neuromuscular Imaging Group

    The group works on different projects concerning nerve imaging, particularly high-resolution ultrasound in neuromuscular disorders ...more information

  • Tabatabai Lab

    Laboratory for Clinical and Experimental Neuro-Oncology

    The Interdisciplinary Division of Neuro-Oncology at the Hertie-Institut for Clinical Brain Research is the result of the, in the context of the Excellent Initiative, newly created W3-Professorship in Neuro-Oncology ... more information

  • Kühn Lab

    Translational Imaging of Cortical Microstructure

    My Research Group uses translational MR imaging to understand how cortical microstructure links to human brain function in health and disease... more information

Research groups

  • Schöls Lab

    Section for Clinical Neurogenetics

    Neurogenetic diseases like cerebellar ataxia, hereditary spastic paraplegia and leukodystrophy are rare disorders. ...more information

  • Thier Lab

    Cognitive Neurology

    The lab addresses a variety of topics that, at first glance, may look disparate. Yet, there is a common denominator ...more information

  • Schüle Lab

    Genomic of Rare Movement Disorders

    Our group specializes in rare diseases. A disease is called rare, when it affects no more than 5 of 100,000 people. However, in the grand-scheme of things, rare diseases are not quite so rare ...more information

  • Giese Lab

    Section for Computational Sensomotorics

    The Section for Computational Sensomotorics investigates theoretical principles in the perception and control of motor actions. Research is organized around three main topics ...more information

  • Karnath Lab

    Section for Neuropsychology

    The Section for Neuropsychology focuses on the investigation of spatial cognition and object recognition in humans. The current issues of our work comprise the action control and sensorimotor coordination ...more information

  • Kahle Lab

    Functional Neurogenetics

    Age-related neurodegenerative diseases are a severe and increasingly worrisome burden for our aging population. Most of the chronic neurodegenerative diseases ...more information

  • Schwarz Lab

    Systems Neurophysiology Lab

    The overarching goal of our work is to understand the operating principles of the neocortex, a unique brain structure, which mainly evolved in mammals. There is clear evidence that the neocortex, in the broadest sense, endows the subject with cognitive capabilities. ...more information

  • Weiß Lab

    Deep Brain Stimulation

    The working group aims to uncover mechanisms of action of deep brain stimulation therapy and to translate the pathophysiological insights into future developments. …more information

  • Häufle Lab

    Motor Control Modeling

    The research group „Multi-Level Modeling in Motor Control and Rehabilitation Robotics“ focuses on the generation and control of active biological movements. We develop ...more information

  • Merk Lab

    Experimental Pediatric Neuro-Oncology

    Brain tumors are the leading cause of cancer-related deaths in infants, children, and adolescents. Our lab is mostly focusing on embryonal brain tumors including ... more information

  • Snaidero Lab

    Neuron-Glia Interactions

    The goal of the Snaidero lab is to decipher and control cellular interactions between neurons and glia cells in the cortex, focussing on the dynamic processes underlying myelination. ... more information

  • Renovanz Lab

    Health Care Research in Neuro-Oncology

    The group focuses on the health-related quality of life, psychosocial burden and unmet needs in neuro-oncological patients. Our key question is... more information

  • Synofzik Lab

    Translational Genomics of Neurodegenerative Diseases

    The translational research of our Research Division is fully geared by a systematic translational pipeline of developing therapy strategies for a broad range of genetically stratified neurodegenerative diseases ...more info

-HIH DZNE Lunch Seminar
The next HIH DZNE Lunch Seminar will take place on Monday, July 1, at 1pm:

Talks:

13:00 Daniel Merk: CRISPR-Cas9 knockout screens: standard approaches and future directions for target identification in cancer
13:20 Stefan Hauser: Using iPSC-based models to develop treatment strategies for monogenic neurodegenerative diseases
13:40 Uwe Ilg: Pupil Lab for Neuroscience: Seeds for the Next Generation

Location: DZNE Seminar room

Combining excellent research and patient care

Click on the image to watch the video