I. Observational Cohort Studies
The goal of our observational and biomarker studies is the stratification of patients according to clinical features, imaging patterns and genetic architecture, in…
Parkinson's disease (PD) is characterized by α-synuclein-positive aggregates in the form of Lewy bodies and Lewy neurites. Point mutations, as well as duplications and triplications of the SNCA gene…
Philipp Kahle is head of the Functional Neurogenetics group at the HIH/DZNE Tübingen. Research aims at the understanding of neuropathological and epigenetics mechanisms of α-synuclein as well as…
Inga Liepelt-Scarfone is a neuropsychologist. As head of the Integrated Clinical and Research Unit (ICRU) of the DZNE Tübingen, she is responsible for a seemless workflow in numerous clinical…
Mutations in the gene encoding PINK1 cause early onset Parkinson's disease. PINK1 is a mitochondrial kinase that acts as a cellular stress sensor and is an upstream component of several signaling…
